Last year scientists found how vitamin D produced in the skin regulates the immune system and triggers certain reactions that kill the germs that cause tuberculosis.
Kappelman thinks that theory could not only explain how the Kocabas male contracted tuberculosis but may also shed light on human migration.
"We found from medical literature that [modern] people who have migrated from southern latitudes—and are more likely to have a darker skin color—to more northern latitudes show a higher incidence of tuberculosis, and that appears to be linked to a vitamin D deficiency," Kappelman said.
After a presumably dark-skinned population of Homo erectus had migrated north, his team's theory holds, the young male in Kocabas was unable to generate enough vitamin D from the reduced sunlight, and a tuberculosis infection proved fatal.
Spencer Wells is a National Geographic Explorer-in-Residence who was not involved in the current study. (National Geographic News is a division of the National Geographic Society.)
Wells said the findings suggest that tuberculosis "might have been the scourge of the hominid lineage for much longer than we suspected."
But he added that he is not convinced darker skin predisposes people to tuberculosis.
Present-day immigrant communities have higher rates of infection due to their lower socioeconomic status and more cramped housing, he said.
Moreover, Homo erectus fossils as old as 1.8 million years have been excavated from Dmanisi, Georgia, he added.
(Read related story: "Odd Fossil Skeletons Show Both Apelike and Human Traits" [September 19, 2007].)
"Compared to this [Turkish] specimen, which is about 500,000 years old, [the Georgian specimens] had 1.3 million years to evolve lighter skin.
"Certainly they would have done it if it was a major selective pressure," said Wells, who also heads National Geographic's Genographic Project.
Kappelman said such an adaptation may well have occurred if the population had stayed north. But the migrants were likely unable to remain due to the severity of cold glacial stages at the time, he said.
"We think there were probably multiple population migrations from southern latitudes to the north, but those early populations were pushed back south during times of extreme climate," he said.
Colin Groves, an anthropologist at Australian National University in Canberra, agreed.
"They were not permanent residents, and their range contracted back into Africa when the ice sheets swept south into Europe," he said.
Each time the climate improved, a fresh population would migrate north, readapting to the conditions, he added.
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